Most runs in IPL 2021
| Player | Team | M | Inn | Runs | Ave | SR |
|---|---|---|---|---|---|---|
| 1Ruturaj Gaikwad | Chennai Super Kings | 10 | 10 | 353 | 39.22 | 128.36 |
| 2Shubman Gill | Kolkata Knight Riders | 10 | 10 | 331 | 33.10 | 118.21 |
| 3Venkatesh Iyer | Kolkata Knight Riders | 9 | 9 | 329 | 36.56 | 126.05 |
| 4Lokesh Rahul | Punjab Kings | 6 | 6 | 302 | 60.40 | 154.08 |
| 5Nitish Rana | Kolkata Knight Riders | 10 | 10 | 239 | 34.14 | 121.32 |
| 6Rahul Tripathi | Kolkata Knight Riders | 10 | 10 | 215 | 26.88 | 143.33 |
| 7Rishabh Pant | Delhi Capitals | 7 | 7 | 196 | 39.20 | 125.64 |
| 8Prithvi Shaw | Delhi Capitals | 7 | 7 | 195 | 27.86 | 158.54 |
| 9Sanju Samson | Rajasthan Royals | 5 | 5 | 194 | 48.50 | 148.09 |
| 10Suryakumar Yadav | Mumbai Indians | 7 | 7 | 192 | 27.43 | 150.00 |
| 11Ambati Rayudu | Chennai Super Kings | 9 | 9 | 169 | 28.17 | 129.01 |
| 12Ishan Kishan | Mumbai Indians | 5 | 5 | 160 | 40.00 | 192.77 |
| 13Shreyas Iyer | Delhi Capitals | 7 | 7 | 157 | 39.25 | 102.61 |
| 14Devdutt Padikkal | Royal Challengers Bengaluru | 3 | 3 | 132 | 44.00 | 110.00 |
| 15Shimron Hetmyer | Delhi Capitals | 6 | 6 | 129 | 25.80 | 159.26 |
| 16Quinton de Kock | Mumbai Indians | 5 | 5 | 120 | 24.00 | 112.15 |
| 17Robin Uthappa | Chennai Super Kings | 4 | 4 | 115 | 28.75 | 136.90 |
| 18Saurabh Tiwary | Mumbai Indians | 4 | 4 | 115 | 57.50 | 118.56 |
| 19Dinesh Karthik | Kolkata Knight Riders | 9 | 9 | 108 | 18.00 | 117.39 |
| 20Suresh Raina | Chennai Super Kings | 6 | 6 | 106 | 21.20 | 137.66 |
| 21Kane Williamson | Sunrisers Hyderabad | 6 | 6 | 103 | 20.60 | 91.96 |
| 22Aiden Markram | Punjab Kings | 4 | 4 | 100 | 25.00 | 117.65 |
| 23Manish Pandey | Sunrisers Hyderabad | 3 | 3 | 99 | 49.50 | 123.75 |
| 24Virat Kohli | Royal Challengers Bengaluru | 3 | 3 | 97 | 32.33 | 124.36 |
| 25MS Dhoni | Chennai Super Kings | 9 | 9 | 95 | 15.83 | 98.96 |
| 26Mayank Agarwal | Punjab Kings | 5 | 5 | 93 | 18.60 | 117.72 |
| 27Hardik Pandya | Mumbai Indians | 5 | 5 | 87 | 29.00 | 110.13 |
| 28Rahul Tewatia | Rajasthan Royals | 5 | 5 | 87 | 17.40 | 96.67 |
| 29Jason Holder | Sunrisers Hyderabad | 6 | 6 | 81 | 16.20 | 120.90 |
| 30Kieron Pollard | Mumbai Indians | 7 | 6 | 75 | 15.00 | 115.38 |
| 31Jos Buttler | Rajasthan Royals | 2 | 2 | 74 | 37.00 | 154.17 |
| 32Priyam Garg | Sunrisers Hyderabad | 4 | 4 | 72 | 18.00 | 98.63 |
| 33Ravindra Jadeja | Chennai Super Kings | 9 | 6 | 72 | 24.00 | 107.46 |
| 34Glenn Maxwell | Royal Challengers Bengaluru | 3 | 3 | 66 | 22.00 | 126.92 |
| 35Shivam Dube | Rajasthan Royals | 4 | 4 | 61 | 15.25 | 96.83 |
| 36Krunal Pandya | Mumbai Indians | 6 | 5 | 53 | 13.25 | 117.78 |
| 37Sunil Narine | Kolkata Knight Riders | 9 | 6 | 52 | 13.00 | 162.50 |
| 38Axar Patel | Delhi Capitals | 7 | 6 | 40 | 8.00 | 86.96 |
| 39David Warner | Sunrisers Hyderabad | 3 | 3 | 39 | 13.00 | 90.70 |
| 40Ravichandran Ashwin | Delhi Capitals | 7 | 4 | 37 | 18.50 | 97.37 |
| 41Harpreet Brar | Punjab Kings | 3 | 2 | 32 | 86.49 | |
| 42Marcus Stoinis | Delhi Capitals | 3 | 2 | 32 | 16.00 | 100.00 |
| 43Riyan Parag | Rajasthan Royals | 3 | 3 | 30 | 10.00 | 120.00 |
| 44Andre Russell | Kolkata Knight Riders | 3 | 2 | 29 | 14.50 | 96.67 |
| 45Shahbaz Ahmed | Royal Challengers Bengaluru | 2 | 2 | 27 | 13.50 | 117.39 |
| 46Evin Lewis | Rajasthan Royals | 1 | 1 | 24 | 24.00 | 126.32 |
| 47Nicholas Pooran | Punjab Kings | 5 | 5 | 22 | 4.40 | 146.67 |
| 48Shivam Mavi | Kolkata Knight Riders | 6 | 1 | 20 | 20.00 | 153.85 |
| 49Mahipal Lomror | Rajasthan Royals | 1 | 1 | 19 | 19.00 | 79.17 |
| 50Lockie Ferguson | Kolkata Knight Riders | 7 | 3 | 18 | 163.64 |
Qualification: no minimum; ties are ordered by name.